pentobarbital will reduce the level or outcome of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust CYP3A4 inducers can lead to decreased serum concentrations and lack of antimalarial efficacyPhenobarbital lowers the plasma amounts of dicumarol (title Beforehand applied: bishydroxyc